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Doxazosin remains a commonly used antihypertensive medication, although its use has been tainted by recent findings from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). The study is based on doxazosin mesylate (the active ingredients of Doxazosin mesylate). 05 for fasting values) and subcutaneous abdominal. The phase IV clinical study analyzes which people take Doxazosin mesylate and have Heart palpitations Doxazosin was recently withdrawn from this trial after an interim analysis showed the secondary end point of combined cardiovascular disease to be 25% greater in patients on doxazosin than in those. Resting heart rate with doxazosin was significantly higher than with urapidil ( P < 0. "Like other alpha-blockers, doxazosin has been associated with significant decreases in total and LDL serum cholesterol and serum triglycerides. Other side effects not listed may also occur in some patients Doxazosin is used in the treatment of BPH and high blood pressure. Swelling of the breasts or breast soreness in both females and males. Redness of the face, neck, arms and occasionally upper chest. ) Doxazosin is used in the treatment of BPH and high blood pressure. Data from ALLHAT (which led to the discontinuation of the doxazosin-treatment arm of. There was a small but significant rise in serum creatinine (mean value, 35 mumol/l) in the group as a whole over a mean period of 75 days Both doxazosin and urapidil decreased blood pressure to the same extent. 02) and forearm blood flow (p < 0. Heart rate increased is found among people who take Doxazosin mesylate, especially for people who are male, 60+ old, have been taking the drug for < 1 month. Trials have shown that lowering blood pressure reduces the risk of a stroke, myocardial infarction (heart attack), and other cardiovascular events. The phase IV clinical study analyzes which people take Doxazosin mesylate and have Heart rate increased Compared to placebo, resting heart rate was significantly increased by doxazosin (+25%, P < 0. Resting heart rate with doxazosin was significantly higher than with urapidil (P < 0. I don't feel dizzy but have shortness of breath, sometimes think I forget to breathe (? This beneficial effect on the lipid profile may be important in some patients with ischemic heart disease. Similarly, the rate pressure product (RPP) at rest was increased by doxazosin (+17%, P < 0. Doxazosin's effects on blood pressure are more significant when standing. Dosage of drugs is not considered in the study. ALLHAT was a large, simple trial, designed in a fashion to closely mimic clinical practice as it occurs in high-risk. Does not adversely affect blood lipid (cholesterol) levels Abstract. ), feeling of anxiousness in my chest, which eases off a little with deep breaths. Out and about during the day I feel fine Pulse rate, blood pressure, forearm and subcutaneous adipose tissue blood flow were measured before and for 6 h after a mixed meal, with concomitant measurements of blood metabolites and insulin. 05) but not by urapidil (+12%, n. Does not adversely affect blood lipid (cholesterol) levels Heart rate was increased by 4 beats/min (mean maximum change); this was statistically, but not clinically, significant. 05) but not by urapidil (+6%, n. Trouble in holding or releasing urine. Other side effects not listed may also occur in some patients Compared to placebo, resting heart rate was significantly increased by doxazosin (+25%, P < 0. Compared to placebo, resting heart rate was significantly increased by doxazosin (+25%, P < 0. ) Heart rate increased in Doxazosin mesylate How the study uses the data? Doxazosin increased pulse rate (p = 0. Heart rate was increased by 4 beats/min (mean maximum change); this was statistically, but not clinically, significant. 01 in fasting state), and decreased vascular resistance in forearm (p < 0. Over the years the dosage of doxazosin was increased to 2x4mg in the morning taken with 1 Bendro and then another 4mg of Dox at night. Other drugs that have the same active ingredients (e. Doxazosin mesylate and Heart palpitations - a phase IV clinical study of FDA data Summary: Heart palpitations is found among people who take Doxazosin mesylate, especially for people who are male, 60+ old, have been taking the drug for < 1 month.